ESPE Yearbook of Paediatric Endocrinology

Scientific Reports (2022)12:3135 doi: 10.1038/s41598-022-07122-6Brief Summary: This case cohort study, based on the Danish National Birth Cohort (DNBC) with ~100 000 women and their children, investigated whether maternal smoking in pregnancy is associated with child BMI and risk for child overweight, independent of maternal pre-pregnancy BMI, genetic predisposition to adiposity and socio-...

Premium research efforts, encompassing laboratory, translational, clinical studies and clinical trials, continually augment our understanding of skeletal biology, along with disorders associated with growth plate, bone, and mineral metabolism. This progression is currently offering innovative treatments for rare skeletal disorders. In this chapter, we underscore several promising clinical trials, notably: a phase 2 study investigating denosumab treatment for fibrous dysplasia,...